Short courses
Health & Social Care

Advanced Pathophysiology

University Certificate in Postgraduate Continuing Education:

This award is specifically for practitioners employed in advanced practice roles to advance their competence in the clinical reasoning required for diagnostics by drawing on pathophysiological principles to support diagnostic analysis.

Course information

Part-time

  • 12 weeks

More part-time details

  • Credits: 20, Level: Master's
  • Enrolment date: October and February
  • Admission enquiries: 01642 384176
  • Fee for UK/EU applicants: £510

Contact details

Further information

The award is twinned with the clinical skills and prescribing awards as these help guide clinical judgement for clinical skills and prescribing in providing the rationale for common signs and symptoms of disease and helping formulate differential diagnosis within the scope of advanced practice. However the award can also be undertaken as a single award in its own right, as can the clinical skills and prescribing awards. Clinical skills at this level are not just about skills, but are more about finding out what the patients symptom burden is, what the pathology is, the extent of the pathology and comorbidity, and so the prognosis for the patient. Given this information the best treatment option in the circumstances can be decided upon in order to help the patient as best we can as health care professionals.

Safe and effective practitioner practice at this level demands a thorough understanding of common disease processes and the dynamics of treatment at cellular, organ and multisystem levels in order to deliver good patient centred care. Focus is on the common mechanisms by which cells, tissues and organs are injured and on the structural changes that underlie these disease processes with strong emphasis being placed on the context in which they might appear in the realities of clinical practice. This award explores pathophysiology from an advanced practitioner perspective, offering the scientific knowledge and practical guidance a practitioner needs to refine diagnosis and make optimal treatment decisions for patients in any setting. Key mechanisms of disease are examined to advance the practitioners knowledge of pathophysiological principle alongside current scientific research in the context of the diagnostics and therapeutics.

The award encompasses the scientific exploration of the following concepts as they relate to advanced practitioner practice:

  • The epidemiological burden of disease for the NHS and the common diseases.
  • The role of the clinical method in establishing differential diagnosis, pathology and aetiology.
  • Homeostatic disturbance and the acute and chronic spectrum of disease as applied to diagnostic triage.
  • Disease trajectories in acute and chronic disease and fraility.
  • Applying the clinical method to recognise patients at risk of systematic homeostatic disturbance in any setting.
  • The common mechanisms of disease.
  • Cell injury and cellular responses to homeostatic stress and ageing.
  • Disorders of vascular flow and shock.
  • The hypoxic energy crisis and ischaemic cell injury as applied to body organs.
  • Pathophysiology of organ system dysfunction, end organ damage and organ system failure at the cellular level.
  • The principles of haemodynamics and the determinants of tissue oxygenation and perfusion.
  • Optimising organ perfusion.
  • Pathophysological processes in infectious illness.
  • Acute and chronic inflammation - immunodefiency and immunoparalysis.
  • Septic shock and the systemic inflammatory response syndrome.
  • The molecular biology of cancer.
  • Metabolic disturbance, dysfunction and failure of negative feedback mechanisms.
  • Haemostatic disturbance.
  • The body's response to homeostatic disturbance and disease - survival mechanisms and cellular adaptation to physiological stress in acute and chronic disease.
  • Application of pathophysiological principle to minimise/avoid risk and reduce patient morbidity and mortality and improve patient outcomes.

How you learn

The award is delivered by short lecture and case based diagnostic analysis sessions to illustrate the multisystem nature of the pathophysiology of common diseases. Practitioners are also able to access additional learning materials from e-learning@tees.

How you are assessed

You are assessed by a summative seen examination. The exam focuses on key presentations of the common diseases encountered in advanced practice, and its unique design allows the advanced practitioner to focus on the key clinical knowledge required for their practice area and clinical skills and therapeutic developments.

Career opportunities

Given the current developments in health care and the ever increasing burden of disease, the need for advanced practitioners with diagnostic and therapeutic capacity is increasing quickly. With the knowledge provided by this award and that combined from the clinical skills award there are now many opportunities for advanced practitioners from all professions to evolve their roles in primary care, acute care and specialist care in delegated aspects of the clinicians role to support health care teams to meet the demands of the 21st century.

Entry requirements

You must be a qualified health care professional and have had evidence of recent study at degree or master’s level.

Course information

Part-time

  • 12 weeks

More part-time details

  • Credits: 20, Level: Master's
  • Enrolment date: October and February
  • Admission enquiries: 01642 384176
  • Fee for UK/EU applicants: £510

Contact details

Further information