Melanoma and Parkinson’s Disease: repurposing biomarkers

Biodiscovery

Teesside University has researched the shared mechanisms between melanoma and Parkinson’s disease. The project aimed to identify biomarkers that could be used for both diseases and develop new treatments that address common pathways.

Challenge

Both melanoma and Parkinson’s disease involve complex biological processes, including the misfolding of proteins like alpha-synuclein. The challenge was to identify biomarkers that could be useful in diagnosing and treating both conditions, and to develop therapies targeting these shared mechanisms.


Solution

The research focused on studying alpha-synuclein and other relevant proteins involved in both melanoma and Parkinson’s disease. The team used biochemical analyses and advanced imaging techniques to understand how these proteins behave and how they might be targeted with new treatments. This approach aimed to repurpose existing biomarkers for both diseases.


Impact

The project’s findings could lead to new diagnostic tools and treatments for melanoma and Parkinson’s disease. By identifying common biomarkers and developing targeted therapies, the research has the potential to improve diagnosis and treatment options for patients with either condition. The study also highlights the benefits of interdisciplinary research in addressing complex medical challenges.

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