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Short courses & CPD
Advanced Bioprocess Control, Data and PAT

Advanced Bioprocess Control, Data and PAT

This five-day course provides in-depth training in the benefits, strategies and concepts control in industrial biomanufacturing, including the challenges and operational complexity in maintaining productivity, efficiency, and quality in the bioprocessing environment and on multi-unit production lines.

 

5 days

 
  • Note: For a limited time, enjoy a 50% discount on this programme as part of our partnership with the RESILIENCE Centre of Excellence for UK Medicines Manufacturing Skills.
 

Course overview

For a limited time, enjoy a 50% discount on this programme as part of our partnership with the RESILIENCE Centre of Excellence for UK Medicines Manufacturing Skills.

This course is for engineers, technical staff and managers wishing to develop and extend their current standard control implementations, also scientists and engineers working in broader bio-based industries where the concepts and approaches can be applied.



Our advanced courses are aimed at those who are already working in the bioprocessing and biomanufacturing sector who want to gain a deeper understanding of relevant theory and techniques, understand and experience state-of-the-art techniques and methodologies, and appreciate the current and future challenges in biomanufacturing.

This course moves on from standard control strategies, to demonstrate how operational efficiencies can be achieved through state-of-the-art process automation, control, and process analytical technology (PAT). You will learn about the initial phases of building the control improvement business case, and how the benefits of advanced automation, control and PAT often far outweigh the cost of implementation. The Advanced Control Engineer’s ‘Toolkit’ is discussed in detail to understand how these approaches can be implemented in the development and regulated manufacturing environment.

Learning outcomes:

  • Gain in depth knowledge of the opportunities afforded by process control to maximise productivity, efficiency, and quality in bioprocessing.
  • Use cost-benefit analysis to evaluate state-of-the-art process automation and control.
  • Apply gained knowledge and a ‘Toolkit’ approach to implement improvements in process automation and control in a regulated manufacturing environment.

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Course details

What you study

Module 1 - Perfecting Conventional Control

- Introduction to biotechnology and bioprocessing 
- The systems engineering landscape in bioprocessing
- Instrumentation including PAT
- Control concepts, performance metrics and PID control
- Strategy design in advanced conventional control

Module 2 - Performance Assessment and Quality Improvement

- Control system cost benefit analysis
- Introduction to design of experiments
- Statistical process control methods
- Lean Six Sigma
- Control and automation in the validated environment

Module 3 - Maximising Information from Available Data

- Data pipelining
- Systems modelling concepts
- Data modelling in bioprocessing
- Visualisation of process development bioprocess data from small bioreactors by multivariate data analysis with SIMCA
- Monitoring of production bioprocess data by multivariate data analysis with SIMCA-online

Module 4 - Advanced Approaches: Process Analytical Technologies and Control Opportunities, Benefits, and Implementation

- Process analytical technologies: Process spectroscopy and its role in control improvement
- Process analytical technologies: Online measurement of biomass and case study examples
- Process analytical technologies: Rapid measurements of quality of product
- Automation case study

Module 5 - Bioprocess Simulation and Automation in Development

- Bioprocess simulation
- Bioreactor automation
- Mechanistic modelling of chromatography
- The future of bioprocess automation

How you learn

This four-day course is delivered through a combination of lectures, workshops, and practical sessions. The content covers theoretical aspects and practical techniques in biomanufacturing, including process control, automation, and process analytical technology (PAT).

How you are assessed

No assessment required.

 

Entry requirements

Entry requirements

At least 3 years’ experience within the biomanufacturing industry.

 

Employability

Career opportunities

Completing this course can benefit careers in biomanufacturing, process development, and R&D. It is particularly useful for roles focused on process control, automation, and data analysis in the bioprocessing industry.

 
 

Part-time

2025-26 entry

Fee for applicants:
£2,950

plus VAT

  • Length: 5 days
  • Start date: TBC

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